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Increases in resting heart rate are a recognised class effect of incretin-based therapies and have been reported with GLP-1 receptor agonists more broadly, as reflected in the Summary of Product Characteristics (SmPC) for licensed agents such as semaglutide (Wegovy) and liraglutide (Saxenda)

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Nicotinamide phosphoribosyltransferase regulates cell survival through NAD+ synthesis [PMID: 19661458] Laboratory literature summary: Nicotinamide phosphoribosyltransferase regulates cell survival through NAD+ synthesis in cardiac myocytes

In trials, 6-16% of participants discontinued due to GI adverse events

DOTCAL-D Calcium Levulinate + Vitamin D3 + Vitamin B12 Injection Veterinary Calcium Support CALCIUM LEVULINATE, VITAMIN D3 & VITAMIN B12 INJECTION Description Formulated for professional veterinary use within our veterinary liquid injections portfolio, DOTCAL-D is an advanced injectable calcium supplement combining Calcium Levulinate, Vitamin D3, and Vitamin B12, designed to support optimal mineral absorption, skeletal integrity, and comprehensive metabolic balance in livestock and companion animals